Nuclear Envelope: Nuclear Pore Complexity

Nuclear Envelope: Nuclear Pore Complexity

A new study shows that the filamentous fungus, Aspergillus nidulans, which has a closed mitosis, does not maintain a continuous permeability barrier during mitosis. This work challenges current views of the differences between closed and open mitosis and has implications for understanding mitotic specific changes in the nuclear pore complex and Ran GTPase system in lower eukaryotes.

Update on the Plant Nuclear Envelope and Nuclear Pore Dynamics of the Plant Nuclear Envelope and Nuclear Pore

The nucleus is the most prominent compartment of any eukaryotic cell and home to its genetic information. The nucleoplasm is surrounded by a double membrane system, the nuclear envelope (NE). The outer nuclear membrane (ONM) and the inner nuclear membrane (INM) are separated by the perinuclear space (or periplasmic space; Hetzer et al., 2005). The lipid bilayer of the ONM is continuous with the...

Dynamics of the plant nuclear envelope and nuclear pore.

Nuclear Envelope: Membrane Bending for Pore Formation?

Membrane-shaping proteins known as reticulons help to sculpt the endoplasmic reticulum; recent findings indicate that they also play a role in the formation of nuclear-pore-complex-associated pores in the nuclear envelope.

Analysis of nuclear reconstitution, nuclear envelope assembly, and nuclear pore assembly using Xenopus in vitro assays.

The large and complex eukaryotic nucleus is the arbiter of DNA replication, RNA transcription, splicing, and ribosome assembly. With the advent of in vitro nuclear reconstitution extracts derived from Xenopus eggs in the 1980s, it became possible to assemble multiple nuclei in vitro around added DNA or chromatin substrates. Such reconstituted nuclei contain a nuclear lamina, double nuclear memb...